The present work deals with an Ordinary Differential Equation (ODE) model specifically designed to describe the COVID-19 evolution in Italy. The model is particularised on the basis of National data about the infection status of the Italian population to obtain numerical solutions that effectively...
01a Articolo in rivista
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We consider nonconvex constrained optimization problems and propose a newapproach to the convergence analysis based on penalty functions. We make use of classicalpenalty functions in an unconventional way, in that penalty functions only enter in thetheoretical analysis of convergence while the...
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Cancer stem-like cells (CSCs) have self-renewal abilities responsible for cancer progression, therapy resistance, and metastatic growth. The glioblastoma stem-like cells are the most studied among CSC populations. A recent study identified four transcription factors (SOX2, SALL2, OLIG2, and POU3F2...
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The Cancer Genome Atlas database offers the possibility of analyzing genome-wide expression RNA-Seq cancer data using paired counts, that is, studies where expression data are collected in pairs of normal and cancer cells, by taking samples from the same individual. Correlation of gene expression...
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The SARS-CoV-2 pandemic is a worldwide public health emergency. Despite the beginning of a vaccination campaign, the search for new drugs to appropriately treat COVID-19 patients remains a priority. Drug repur-posing represents a faster and cheaper method than de novo drug discovery. In this study...
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Novel technology has been applied to improve students’ learning abilities in different disciplines. The research in this field is still finding suitable methodologies, tools, and evaluation mechanisms to devise learning frameworks with high impact on students’ performance. This article describes an...
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Modeling the arrival process to an Emergency Department (ED) is the first step of all studies dealing with the patient flow within the ED. Many of them focus on the increasing phenomenon of ED overcrowding, which is afflicting hospitals all over the world. Since Discrete Event Simulation models are...
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The paper deals with topology-induced containment output feedback for ensuring multi-consensus of homogeneous linear systems evolving over a weakly connected communication digraph. Starting from the extension of a recent characterization of multi-consensus, a decentralized static feedback enforcing...