Introduction: Only a minority of patients with platinum refractory head and neck squamous cell carcinoma (PR/HNSCC) gain some lasting benefit from immunotherapy. Methods: The combined role of the comprehensive genomic (through the FoundationOne Cdx test) and immune profiles of 10 PR/HNSCC patients...
01a Articolo in rivista
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Breast cancer (BC) is a heterogeneous and complex disease characterized by different subtypes with distinct morphologies and clinical implications and for which new and effective treatment options are urgently demanded. The computational approaches recently developed for drug repurposing provide a...
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Detecting niches of polarization in social media is a first step towards deploying mitigation strategies and avoiding radicalization. In this paper, we model polarization niches as close-knit dense communities of users, which are under the influence of some well-known sources of misinformation, and...
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When dealing with complex functional brain networks, group analysis still represents an open issue. In this paper, we investigated the potential of an innovative approach based on PARAllel FActorization (PARAFAC) for the extraction of the grand average connectivity matrices from both simulated and...
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The main protease (M-pro) of SARS-Cov-2 is the essential enzyme for maturation of functional proteins implicated in viral replication and transcription. The peculiarity of its specific cleavage site joint with its high degree of conservation among all coronaviruses promote it as an attractive...
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Graph neural networks have proved to be a key tool for dealing with many problems and domains such as chemistry, natural language processing and social networks. While the structure of the layers is simple, it is difficult to identify the patterns learned by the graph neural network. Several works...
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The fifth generation (5G) of mobile networks is designed to mark the beginning of the hyper-connected society through a broad set of novel features and disruptive characteristics, delivering massive connectivity, coverage and availability paired with unprecedented speed, throughput and capacity....
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Authoring and Reviewing Bibliographies: Design and Development of a Visual Analytics Online PlatformResearchers are daily engaged in bibliographic tasks concerning literature search and review, both in the role of authors of scientific papers and when they are reviewers or evaluators. Current indexing platforms offer powerful tools for searching bibliographic references, but in general they...
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Aggregation is common in data analytics and crucial to distilling information from large datasets, but current data analytics frameworks do not fully exploit the potential for optimization in such phases. The lack of optimization is particularly notable in current "online"approaches that store data...
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