 In the episode "Finding Nimmo" there is a reference to William  Shatners career in Star Trek. While resting in the cabin, Alan  Shore (James Spader) mentions to Denny (Shatner) that there are  parasites called "Klingons". Denny reacts with a shocked look and  says "Did you say Klingons?" There are also other references to Star  Trek in other episodes. Some examples being Dennys cell phone and a  metal detector making the communicator chirp and Denny saying "What  am I supposed to do, beam to Boston everyday?"