 The title of the show is essentially meaningless. The comic strip on  which the show is based was written by Azuma Kiyohiko, and  "Azumanga" is an amalgalm of his name and "manga", the Japanese word  for comic books. "Daioh" comes from "Dengeki Daioh" ("Great Electric  Shock King"), the monthly Japanese comic anthology in which the  comics originally ran.