 Patrick Duffy, George Clooney (qv), Jay Leno (qv),  Jennifer Aniston (qv), and Robert Smith (III) (qv) (lead singer  of "The Cure") accepted roles on the show. Samuel L. Jackson (qv),  Steven Spielberg (I) (qv), Jerry Seinfeld (qv),  Steve Buscemi (qv), and Jeff Daniels (I) (qv) asked to do guest  voices, but were either rejected or declined the offer afterward.  Stone and Parker also asked  _"Mr. Show with Bob and David" (1995)_ (qv) alumni  Tom Kenny (I) (qv), David Cross (II) (qv), Bob Odenkirk (qv),  Brian Posehn (qv), and John Ennis (I) (qv) as well as  _"Family Guy" (1999)_ (qv) voice talent Seth MacFarlane (qv) to do  guest voices, but all declined because their shows were doing well  (Mr. Show has since been canceled, and MacFarlane again declined due  to other commitments).