 SPOILER: David Shore (I) (qv) has said that the character of House  is inspired by the fictional character Sherlock Holmes, particularly  with regard to drug use and his desire (and capacity) to solve the  insolvable. House uses Holmesian deductive techniques to diagnose  his patients problems. References to the sleuth range from the  obvious (Houses apartment number being 221B) to the subtle (his  friendship with Dr. James Wilson and the similarities between the  names House and Holmes, and Wilson and Watson). In the very first  (pilot) episode the patients last name is Adler, and in the last  episode of season two, the last name of the man who shot House is  Moriarty. Houses act of faking cancer in "Half