 SPOILER: Five different actresses have played Laura Bristow/Irina  Derevko. Arabella Holzbog played Laura Bristow in a picture Sydney  kept. Kate Anthony was the voice of Irina Derevko in the video clip  shown in episode 1.19, "Snowman". Natasha Pavlovich is the woman we  actually see as Irina Derevko in that video clip. April Webster  played Irina when she walks up to Sydney at the end of episode 1.21,  "Almost Thirty Years". Finally, Lena Olin played Irina Derevko for  the second season and beyond. Additionally, in Season 4, episode 18,  Sydney Bristow (Garner) briefly portrays her mother (Laura Bristow)  so they can learn information from her father.