 It seems like just another ordinary day in Seattle Grace Hospital until tragedy strikes Izzie Stevens.To her dismay,the adoptive parents of her eleven year old daughter reveal a terrible truth.Her eleven year old daughter is also a leukemia patient.Deeply saddened by this news,her eleven year old daughter s adoptive parents also tell Izzie that she should donate some of her bone marrow to the girl.Because it is likely that it will be a "perfect match"...... Also the race to be "chief of surgery" tears Meredith and Derik s relationship apart.