 When Piper opens a kiwano, an escaping sand fly infects her with a tropical fever too bad for medicine to cure. Her sisters brave the wiccan  no personal gain -rule to save her by a spell, but the puppet the disease went into spreads the now contagious infection, so they are soon quarantined as medical mystery. The only way out is to reverse the spell, at the cost of Piper life - or can Leo help? Prue decides t break with her job and Jack now her finding a picture is not by Monet himself is disregarded.