 After a mysterious and bloody airplane crash, 48 survivors are left stranded on a Pacific Island... miles off course. It soon becomes apparent that they will not have to cope only with the forces of nature, but with the island s secrets, including the Dharma Initiative, the  Lost Numbers , the "others" (or hostiles) and the strange black smoke- to name a few. There is also much more than meets the eye, as it becomes apparent that everyone is connected in some way and that everyone has a purpose to live on the island... and for some, to die.