 Barowner Joe collapses in his bar and needs to undergo an 200.000$ surgery to survive. Since Joe has no insurance George tries to find a way to get the money together. Dr. Webber is recovering from his operation and appointed Burke as his replacement. Burke has now to face the consequences that come with the responsibilities of his new position. The return of his wife Addison puts an end to Derek s relationship with Meredith. Meredith herself is more concerned with the pregnancy of Christina and her secret relationship with Burke.