 After a plane crash with only seven survivors, including the pilot and a stewardess, Dean and Sam are called by the friend of their father Jerry Panowski, who also works in United Britannia Company and shows the last message from the cabin scrambled with an eerie voice saying "No survivals". Dean and Sam interviews a survivor in a psychiatric hospital, who believes that had seen a passenger opening the emergency exit of the plane, which would be impossible for a human being. They investigate the wrecked plane and find sulphur on the lever of the emergency exit and conclude that a fiend had possessed a passenger and caused the crash. When the survival pilot dies in another plane crash, they track the other survivor, the stewardess Amanda Walker, and convince her help them to exorcise the demon from the co-pilot of the flight.