 After years of silence from the Apocolypse INC (from part 2 and 3 of the Toxic Avenger seriers), Apocolypse INC returns to Tromaville under new management, instead of a demon, its an alien from the planet Smogulla known as Dr.Killemoff. Toxie has too battle Apocolypse once more to protect his hometown from the evil spage doers and the fat and corrupted Mayor. But he won t have to do it alone as a group of other mutant superhero s join him in the fight, NoZone, Junkyard, Headbanger, Major Disaster and Toxie become THE TOXIC CRUSADERS.