 After the body of murdered woman is found, nude and handcuffed, floating down the Hudson River in New York, a string of murders occur by an unseen serial killer who kills men by handcuffing them before killing them. Mac, a TV talk-show host, and Larry, a police detective, team up to try to find the killer and seek help from Virna, a clairvayant young artist, who draws visions of the murders before they happen. As Mac and Larry try to establish a connection between the victims and the first female victim, who may have been sexually involved all of the male victims, Virna s further visions begin to point to her as the next victim as she unknowingly closes in on the killer s identity.