 Two brothers, Sam (Jared Padalecki, "Gilmore Girls") and Dean Winchester (Jensen Ackles, "Smallville"), witness their mother s paranormal death as children and grow up trained to fight by a distraught father who wants nothing more than to hunt down the thing that killed his wife. Sam escapes to college to start a new, normal life, but gets pulled back in after Dean shows up on his doorstep to tell him their father is missing. Following clues from their father s eerie phone message, the boys travel to a small town and encounter a violent and vengeful spirit called the "Woman in White."