 Mame is an unconventional individualist socialite from the roaring 20 s. When her brother dies, she is forced to raise her nephew Patrick. However, Patrick s father has designated an executor to his will to protect the boy from absorbing too much of Mame s rather unconventional perspective. Patrick and Mame become devoted to each other in spite of this restriction, and together journey through Patrick s childhood and the great depression, amidst some rather zaney adventures.