 After Kyle gets sick, his mother hears about spiritual remedies from Stan s mother, and so begins taking Kyle for one quack remedy after another (from the new spiritual therapist in town, Miss Information) instead of getting him medical treatment. When she finally does take Kyle to a doctor, he tells them that Kyle s kidneys are failing and that he will need a transplant in order to survive. Unfortunately for Kyle, the only suitable donor is Cartman, who refuses to help him. Meanwhile, Mr. Garrison, having been fired for soliciting little Cartman for sex in the previous episode, decides to write a romance novel, "The Valley of the Penises."