 The fifth daughter of a wealthy Boston physician, Michaela Quinn defies the conventions of post-Civil War society by following in her father s footsteps. After his death,  Dr. Mike  leaves Boston and moves to the frontier town of Colorado Springs, where she finds the citizens less than thrilled by the concept of a woman doctor. While she struggles to earn their trust, Mike s life is complicated by a growing relationship with mountain man Byron Sully, and the unexpected responsibility of raising three orphaned children.