 The year is 2210. The universe is overrun with hundreds of vampire species that prey upon humans in brutal, surprise attacks. That s when intergalactic Vampire Sanitation teams are called upon to lay waste to these vile predators. V-SAN crews, who ve come to know their line of work as "the toughest job you ll ever hate," are comprised of rough and rugged men, women-and in the case of the Heironymous crew-a half human-half vampiress named Quintana (Natassia Malthe), who draws upon her psychic prowess to help the V-SANs track their quarry. Led by Captain Nicholas Churchill (Joe Lando) and second-in-command Damian Underwood (Dominic Zamprogna), the Heironymous team becomes the target of a deadly trap that has a much deeper and darker purpose. Directed by their vile leader Muco (Michael Ironside), the vampires have no plans of living peaceably with humans...they want to rule the universe.