 Skye Quartermaine headlines a show about the residents of Port Charles, NY. Once a show about the drama inside a city hospital, General Hospital has evolved into a show where the hospital has been nearly phased out. Stories focus on the upper-crust Quartermaines, led by Skye Quartermaine, her brothers AJ and Jason, father Alan, stepmother Monica, and grandparents Edward and Lila. Other stories involve mob boss Sonny Corinthos, his wife Carly, and one-time girlfriend Brenda.