 A escape pod containing a "Microbe" a genetically-engineered virus that eats metal and programmed not to harm glass has arrived on-board "Red Dwarf" and begins to eat away Red Dwarf. Left on-board "Red Dwarf" to die, Rimmer, Lister, Cat, Kryten, Kochanski and Holly find their own chance at finding a antidote is in a mirror universe where everything is opposite, and Rimmer is sent into the Mirror universe to find the antidote before Red Dwarf is destroyed along with Lister, Kryten, Cat and Holly.